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Jan 29, - So what's the difference with the way that these two drugs work? With both Klonopin and Ativan, its Clonazepam content affects chemicals in the brain which may have become unbalanced, and cause anxiety. The most common use of Klonopin is for seizure disorders and panic disorders, while Ativan is. Dec 22, - I'd have to agree with you, I can see the starting dose for clonazepam being.5mg twice a day. I forget what color they are (Yellow?) either that or blue. The 1mg's are green. People call them "green monsters" lol but I don't. Klonopin helps you keep your day going basically, ativan would only help more with. Jun 3, - Varying durations of action - Due to differences in half-life, active metabolites, and drug accumulation, benzodiazepine conversions should account for single-dose A commonly cited double-blind trial suggests a conversion of 1 mg IV lorazepam to 2 mg of IV midazolam, which is further supported using a.