Tag Archives: Depression

FDA Supports Intravenous Brexanolone for Postpartum Depression

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed with moderate to severe postpartum depression. This… Read More »

Medical News Today: Major depression: Existing drug reduces symptoms by 45 percent

For the first time in decades, researchers have identifed a new medication that can successfully treat major depression. An existing oral drug may relieve major depression. Depression affects about 300 million people across the globe, making the condition the “leading cause of ill health and disability worldwide,” according to the World Health Organization (WHO). In… Read More »

Alkermes' depression treatment fails to get FDA panel backing

(Reuters) – An advisory panel to the U.S. Food and Drug Administration on Thursday voted against approving Alkermes Plc’s treatment for depression in patients with an inadequate response to standard antidepressant therapies. The decision comes two days after FDA staff reviewers bit.ly/2QegxPF flagged abuse potential for the opioid-based depression treatment and raised questions on its… Read More »