Active Ingredient: Gabapentin
Patients can experience persistent pain that is not well controlled.
There are clinical, psychological, and social consequences associated with chronic pain including limitations in complex activities, lost work productivity, reduced quality of life, and stigma, emphasizing the importance of appropriate and compassionate patient care 4.
Patients should receive appropriate pain treatment based on a careful consideration of the benefits and risks of treatment options. Chronic pain can be the result of an underlying medical disease or condition, injury, medical treatment, inflammation, or an unknown cause 4.
Estimates of the prevalence of chronic pain vary, but it is clear that the number of persons experiencing chronic pain in the United States is substantial.
Based on a survey conducted during — 7, the overall prevalence of common, predominantly musculoskeletal pain conditions e. Most recently, analysis of data from the National Health Interview Study showed that 11.
Clinicians should consider the full range of therapeutic options for the treatment of chronic pain.CDC developed the guideline using the guideline provides recommendations for primary care Evaluation GRADE framework, and recommendations are chronic pain outside of active cancer treatment, palliative care, and end-of-life care. Free Medscape CMEexternal icon Summary This Grading of Recommendations Assessment, Development, and clinicians who are prescribing opioids for made on the basis of a systematic review of the scientific evidence.
However, it is hard to estimate the number of persons who could potentially benefit from opioid pain medication long term.
On the basis of data available from health systems, researchers estimate that 9. Opioid pain medication use presents serious risks, including overdose and opioid use disorder.
From 1999 to, more than 165,000 persons died from overdose related to opioid pain medication in the United States 16. In the past decade, while the death rates for the top leading causes of death such as heart disease and cancer have decreased substantially, the death rate associated with opioid pain medication has increased markedly 17.
Sales of opioid pain medication have increased in parallel with opioid-related overdose deaths 18. Although clinical criteria have varied over time, opioid use disorder is a problematic pattern of opioid use leading to clinically significant impairment or distress.
Having a history of a prescription for an opioid pain medication increases the risk for overdose and opioid use disorder 22—24, highlighting the value of guidance on safer prescribing practices for clinicians.
For example, a recent study of patients aged 15—64 years receiving opioids for chronic noncancer pain and followed for up to 13 years revealed that one in 550 patients died from opioid-related overdose at a median of 2.
This guideline provides recommendations for the prescribing of opioid pain medication by primary care clinicians for chronic pain i.