Active Ingredient: Gabapentin
Responders from the SB phase patients with improvements on the International Restless Legs Scale and investigator-rated Clinical Global Impression—Improvement scale at week 24 and stable while taking a gabapentin enacarbil dose of 1200 mg for at least 1 month before randomization were randomized to gabapentin enacarbil, 1200 mg, or placebo once daily at 5 pm with food.
The primary end point was the proportion of patients experiencing relapse worse scores on the IRLS and investigator-rated Clinical Global Impression of Change scale on 2 consecutive visits at least 1 week apart or withdrawal because of lack of efficacy during the DB phase.
Ask your doctor about any risk. How should I take Neurontin?
Take Neurontin exactly as prescribed by your doctor. Follow all directions on your prescription label.
Do not take this medicine in larger or smaller amounts or for longer than recommended.
Neurontin can be taken with or without food. If you break a Neurontin tablet and take only half of it, take the other half at your next dose.
Any tablet that has been broken should be used as soon as possible or within a few days. Swallow the capsule or tablet whole and do not crush, chew, break, or open it.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device not a kitchen spoon. Ask your pharmacist if you have any questions about the new kind of gabapentin you receive at the pharmacy.
Follow your doctor's instructions about tapering your dose. Wear a medical alert tag or carry an ID card stating that you have seizures.
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