Active Ingredient: Norfloxacin
Careful monitoring and supportive treatment, monitoring of renal and liver function, and maintaining adequate hydration is recommended by the manufacturer.
At the respective doses, mean peak serum and plasma concentrations of 0.
The effective half-life of norfloxacin in serum and plasma is 3—4 hours. Steady-state concentrations of norfloxacin will be attained within two days of dosing.
Norfloxacin is least soluble at urinary pH of 7. Other companies initiated fluoroquinolone discovery programs in the aftermath of the publication of the norfloxacin patent. Bayer Pharmaceuticals discovered that the addition of a single carbon atom to the norfloxacin structure provided another 4 to 10-fold improvement in activity.
Some people develop thrush redness and itching in the mouth or vagina after taking a course of antibiotics. If you think you have thrush, speak with your doctor or pharmacist for advice. If you are having any vaccinations, make sure the person treating you knows that you are taking this medicine.
Make sure your reactions are normal before you drive, operate machinery or do any other jobs which could be dangerous if you are not sufficiently alert. Can norfloxacin cause problems? Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them.
The table below contains some of the most common ones associated with norfloxacin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common norfloxacin side-effects What can I do if I experience this? Feeling sick nausea or being sick vomiting, indigestion, tummy abdominal pain Stick to simple foods - avoid rich or spicy meals Diarrhoea Drink plenty of water to replace lost fluids.
If you have any further questions on the use of this product, ask your doctor or pharmacist or nurse. Like all medicines, this medicine can cause side effects, although not everybody gets them.
Allergic reactions can, very rarely, be life-threatening. Achilles tendon. Inflammation of the liver with jaundice yellowing of the skin or whites of the eyes commonly occurs. Stop treatment and contact your doctor if you experience signs and symptoms of liver problems such as loss of appetite, jaundice, dark urine, itching or sensitivity to pressure in the abdominal cavity.
If you develop the rare side effect of severe and persistent diarrhoea whilst you are taking your tablets or after stopping your tablets you should consult your doctor.