Active Ingredient: Orlistat
These include obesity, smoking, dyslipidemias, and diabetes, among others. While the statins have changed the outlook for individuals with dyslipidemia, other risk factors, particularly obesity, continue to be difficult to treat pharmacologically, and heart disease and other weight-related maladies remain major causes of morbidity and mortality.
Despite the handful of anti-obesity drugs that have progressed to clinical trials and remain viable candidates for new drug approvals, the opportunity to develop new drugs remains compelling, as most obesity experts expect that more than one drug will be needed to control obesity.
Efficient fat storage, the intricately controlled mechanism that helped mankind survive protracted food shortages, backfires in a well-fed, relatively sedentary society.
When Fat Becomes Fatal While diet and exercise successfully control weight for many individuals, clinicians increasingly recognize that safer, more effective drugs are needed in the war against the current obesity epidemic.
According to the FDA, available drugs induce only modest weight loss 15 kg relative to placebo, diet, and exercise. Further, the emerging view of obesity as a chronic disease with complex pathophysiology likely to require long-term medication for adequate control imposes an additional safety burden on new drugs.
Both drugs produce side effects that discourage long-term use. This represents an incidence of 00038 deaths per patient-year.
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Fourteen patients had an electroretinogram all normal! Preliminary studies on Acomplia for smoking cessation and alcohol and drug treatment are underway.Shadow communities secretary Hilary Benn said. That's not something that consumers appreciate, said Dr.
Metabolic syndrome is a collection of symptoms, including high blood pressure, high cholesterol, large waist circumference, obesity and insulin resistance, that can lead to diabetes and heart disease without treatment.
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